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Tigers vs Guardians Picks, Odds and Prediction

MLB picks: Guardians-Tigers odds, predictions for May 22 from proven model

Will the Detroit Tigers pick up their MLB-leading 34th win of the season when they take on the Cleveland Guardians? Here are the best bets from the SportsLine Projection Model

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Tigers vs. Guardians Prediction, Odds, Picks - May 22

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Where to watch the Tigers vs. Guardians MLB live stream today

Guardians Activate Playoff Hero From Injured List

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Guardians' Lane Thomas activated off IL after missing month

Guardians center fielder Lane Thomas, who hasn't played since April 19 due to an injured right wrist, was activated and will start in Thursday's game vs. the Tigers.

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Guardians activate Lane Thomas, place Will Brennan on 10-day injured list

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Guardians Activate Playoff Hero From Injured List In Recent Roster Moves

Twins, Cleveland Guardians

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Guardians snap 5-game losing streak with 5-1 win over Twins

Gavin Williams pitched six strong innings and José Ramírez had three more hits to extend his hitting streak to 14 games as the Cleveland Guardians beat the Minnesota Twins 5-1 on Wednesday. Steven Kwan was 3 for 5 with two doubles and Carlos Santana added his second home run of the day in the eighth inning as the Guardians

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Guardians-Twins suspended, scheduled games postponed

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Kody Clemens hits walk-off double to give Twins 6-5 win over Guardians in Game 1 of doubleheader

Guardians score vs. Twins: Kody Clemens' walk-off double sinks Cleveland

Carlos Santana homered for the Guardians, who have now lost five in a row.

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Kody Clemens saves Twins with walk-off double, 6-5

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Clemens plays hero with walk-off double in rain-soaked Game 1

Tigers vs. Guardians Starting Pitcher Matchup - May 22

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Cleveland Guardians Blasted for Contentious Offseason Moves

The Cleveland Guardians were very active during the MLB offseason, but not in the way that their fans wanted. Instead of making moves to improve their roster, t

Guardians game with Twins suspended by rain, scheduled to resume at 6:10 p.m. Tuesday

Monday's game between the Cleveland Guardians and Minnesota Twins has been suspended by rain with the Twins leading 2-1 in the fourth inning.

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What Brayan Rocchio is focused on after demotion from Guardians to Triple-A Columbus

The Guardians demoted infielder Brayan Rocchio to Triple-A Columbus on May 12 after struggling in 35 games with Cleveland this season.

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Oblique injury to sideline Guardians top pick Travis Bazzana two months

Travis Bazzana, selected by the Guardians with the first overall pick in the 2024 MLB draft, experienced a setback May 19 that could keep the young second baseman out of the Akron RubberDucks’ lineup until late July or early August. Bazzana was injured ...

Steven Robert Kwan Player Props: May 22, Guardians vs. Tigers

MLB player prop bets and odds for Steven Robert Kwan on Thursday, May 22, 2025, as the Cleveland Guardians take on the Detroit Tigers.

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How Gavin Williams became a Guardians stopper in Minnesota

Cleveland desperately needed to halt a five-game skid, and Gavin Williams delivered one of his best performances of the season.

Guardians' Doug Nikhazy: Sent back to minors

Nikhazy was available as the 27th man for Wednesday's doubleheader against the Twins but did not make an appearance. He will return to the rotation at Columbus, where he's posted a 4.99 ERA and 31:15 K:BB over 30.2 innings covering seven starts.