Risperidone and aripiprazole may reduce irritability symptoms, while lurasidone probably results in little to no difference ...

Sustained-release naltrexone may slightly increase illicit opioid use and serious adverse events compared to opioid agonists, with uncertain effects on retention and acceptability. It may reduce ...

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Compared with placebo, PPIs may have no effect on the presence of global symptoms of dyspepsia and probably result in a slight reduction in global symptoms of dyspepsia scales. PPI probably reduces ...

Level III sleep studies may result in little to no difference in clinical outcomes when compared to Level 1 sleep studies in people with suspected OSA. Level IV sleep studies may not increase ...

To explore the views and experiences of adolescents and youth who engaged with (i.e. were approached for participation) or participated in HIV research in low-and middle-income countries. To develop a ...

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of exercise interventions for work-related complaints of the arm, neck or shoulder (CANS) ...

If you found this evidence helpful, please consider donating to Cochrane. We are a charity that produces accessible evidence to help people make health and care decisions. Borys F, Sibrecht G, ...

The evidence does not currently support a clear benefit or harm for routine intravenous thrombolysis amongst people receiving endovascular thrombectomy. Amongst participants receiving endovascular ...

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缺乏高质量的证据来评价多种疗法治疗CRPS 的有效性。在进行更大规模的试验之前，制定一种以证据为基础的治疗CRPS的方法仍然很困难。 虽然已经描述并常用了多种干预措施，但对于复杂区域 ...

来自RCTs的关于他喷他多有效性和耐受性的信息有限。可用研究的规模中等或较小，且使用了不同的设计，这些因素阻碍了数据的合并。他喷他多与吗啡和羟考酮组的疼痛缓解和不良事件相当。