The Boston Red Sox (30-34) and New York Yankees (38-23) begin a 3-game series Friday. First pitch from Yankee Stadium is set for 7:05 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Red Sox vs. Yankees odds and make our expert MLB picks and predictions for the best bets.

The Guardians surprised the Yankees 4-0 in the middle game Wednesday night, as RHP Luis Ortiz baffled New York with 5 2/3 scoreless innings with 7 strikeouts on 92 pitches, while the bullpen took over and tossed 3 1/3 innings of scoreless baseball with just 2 hits and no walks on 46 pitches.

Preview the June 6 matchup between the New York Yankees and Boston Red Sox with odds over/under, game spread, betting lines and more.